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Xgene Pharmaceutical Inc. engineers high-impact medications for unmet underserved needs in neurological conditions. Xgene’s proprietary linker technology generates novel dual-acting conjugates combining two well-characterized and efficacious therapeutic molecules to produce a targeted multimodal approach. The conjugated prodrug molecules exhibit different – modified by the linker – absorption, pharmacokinetic, and metabolic characteristics as compared to either parent drug. Preclinical studies of these conjugates demonstrate that the Xgene’s linker modification results in lower toxicity and superior efficacy in several conditions characterized by high unmet need.
Field
Biotech
Conjugated molecules
Pain therapeutics